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Sildenafil was detrimental in in vitro bacterial and Chinese hamster ovary mobile assays to detect mutagenicity, As well as in vitro human lymphocytes As well as in vivo mouse micronucleus assays to detect clastogenicity.g., creatinine clearance < 30 mL/min), and concomitant use of erythromycin or strong CYP3A4 inhibitors, plasma amounts of sildena

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